Estimation of extravascular lung water by indicator-dilution techniques.

Estimation of extravascular lung water by indicator-dilution techniques.

Indicator dilution measurements of extravascular water in the lungs.

Multiple indicator dilution studies of the pulmonary circulation were carried out in conscious, resting and exercising, and anesthetized dogs under conditions where there was no pulmonary edema. Labeled red cells, water, and albumin were injected together into the pulmonary artery, and effluent dilution patterns were obtained from the descending thoracic aorta. The product of the mean transit t...

Indicator dilution measurements of extravascular lung water: basic assumptions and observations.

Since they were introduced more than five decades ago, a variety of single-pass indicator, thermal, and osmotic dilution approaches have been developed for detecting and measuring excess fluid in the lungs. This brief review discusses why studies of the extravascular lung water (EVLW) continue to intrigue physiologists and clinicians and the likelihood that they will become sufficiently reliabl...

Invited Review Indicator dilution measurements of extravascular lung water: basic assumptions and observations

Effros RM, Pornsuriyasak P, Porszasz J, Casaburi R. Indicator dilution measurements of extravascular lung water: basic assumptions and observations. Am J Physiol Lung Cell Mol Physiol 294: L1023–L1031, 2008. First published March 21, 2008; doi:10.1152/ajplung.00533.2007.—Since they were introduced more than five decades ago, a variety of single-pass indicator, thermal, and osmotic dilution appr...

Reproducibility of double indicator dilution measurements of intrathoracic blood volume compartments, extravascular lung water, and liver function.

STUDY OBJECTIVE Arterial thermal dye dilution (TDDart) with the COLD system (Munich, Germany) allows measurement of cardiac index (CI), partial blood volumes, lung water, and liver function. The aim of the study was to determine agreement of TDDart measurements with pulmonary artery thermal dilution measurements (TDpa) and to assess the reproducibility of TDDart parameters. DESIGN Prospective...